Michael Kukulka

Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir

Dale J. Kempf, Kennan C. Marsh, Gondi Kumar et al. · Antimicrobial Agents and Chemotherapy · 1997 · 418 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +15

Measurement of Liver Microsomal Cytochrome P450 (CYP2D6) Activity Using [O-methyl-14C] Dextromethorphan

A. David Rodrigues, Michael Kukulka, Bruce W. Surber et al. · Analytical Biochemistry · 1994 · 75 citations

Molecular Pharmacology, Hepatology, Biochemistry +13

In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.

A. David Rodrigues, Darcy J. Mulford, R D Lee et al. · Drug Metabolism and Disposition · 1995 · 70 citations

[O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.

A. David Rodrigues, Michael Kukulka, Ellen Roberts et al. · Drug Metabolism and Disposition · 1996 · 63 citations

The Effect of Age and Gender on Pharmacokinetics, Pharmacodynamics, and Safety of Febuxostat, a Novel Nonpurine Selective Inhibitor of Xanthine Oxidase

Reza Khosravan, Michael Kukulka, Jingtao Wu et al. · The Journal of Clinical Pharmacology · 2008 · 56 citations

Medicinal Chemistry, Urology, Pharmacological Study +13