Hisashi Hidaka

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

Takashi Chijiwa, Akihiko Mishima, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 1.5K citations · Full text

KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II.

Hiroshi Tokumitsu, Takashi Chijiwa, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 625 citations · Full text

Specific Inhibitor, Molecular Biology, Pharmacotherapy +23

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.

Hisashi Hidaka, Yasuharu Sasaki, Toshio Tanaka et al. · Proceedings of the National Academy of Sciences · 1981 · 584 citations · Full text

Chemoprevention Strategy, Cell Death, Cellular Pharmacology +17

Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.

M. Saitoh, Tomohiko Ishikawa, S Matsushima et al. · Journal of Biological Chemistry · 1987 · 509 citations · Full text

MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase.

David Stokoe, David G. Campbell, Sara Nakielny et al. · The EMBO Journal · 1992 · 480 citations · Full text

Signal Transduction, Molecular Physiology, Mapkap Kinase-2 +12