Isabel Soria‐Bretones

Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies

John Hilton, Karen A. Gelmon, Philippe L. Bédard et al. · Nature Communications · 2022 · 145 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma

Cerise Yuen‐Ki Chan, David Kung‐Chun Chiu, Vincent Wai‐Hin Yuen et al. · Proceedings of the National Academy of Sciences · 2022 · 57 citations · Full text

Medicine, Oncology, Pharmacology +17

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair

Keren Baranes‐Bachar, Adva Levy‐Barda, Judith Oehler et al. · Molecular Cell · 2018 · 56 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

DNA end resection requires constitutive sumoylation of CtIP by CBX4

Isabel Soria‐Bretones, Cristina Cepeda-García, Cintia Checa-Rodríguez et al. · Nature Communications · 2017 · 54 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures

Sonia Jimeno, Rosa Camarillo, Fernando Mejías-Navarro et al. · Cell Reports · 2018 · 53 citations · Full text

Life Sciences, Genetics, Molecular Biology +17