Vincent Wai‐Hin Yuen

Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway

David Kung‐Chun Chiu, Aki Pui‐Wah Tse, Cheuk‐Ting Law et al. · Cell Death and Disease · 2019 · 196 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma

Derek Lee, Mingjing Xu, David Kung‐Chun Chiu et al. · Hepatology · 2018 · 175 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Hepatocellular Carcinoma Cells Up-regulate PVRL1, Stabilizing PVR and Inhibiting the Cytotoxic T-Cell Response via TIGIT to Mediate Tumor Resistance to PD1 Inhibitors in Mice

David Kung‐Chun Chiu, Vincent Wai‐Hin Yuen, Jacinth Wing‐Sum Cheu et al. · Gastroenterology · 2020 · 165 citations

Medicine, Cancer Biology, Oncology +17

Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer

Jacinth Wing‐Sum Cheu, Derek Lee, Qidong Li et al. · Cellular and Molecular Gastroenterology and Hepatology · 2023 · 111 citations · Full text

Life Sciences, Immunology, Oncology +15

Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

Misty Shuo Zhang, Jane Di Cui, Derek Lee et al. · Nature Communications · 2022 · 109 citations · Full text

Medicine, Cell Biology, Oncology +17