Priyadarshini Iyer

Identification of (<i>R</i>)-<i>N</i>-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1<i>H</i>-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas

Rishi G. Vaswani, Victor Gehling, Les A. Dakin et al. · Journal of Medicinal Chemistry · 2016 · 220 citations · Full text

Medicine, Oncology, Pharmacology +16

Identification and Characterization of Genes Required for Cell-to-Cell Fusion in Neurospora crassa

Ci Fu, Priyadarshini Iyer, Amrita Herkal et al. · Eukaryotic Cell · 2011 · 186 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +10

EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation

William D. Bradley, Shilpi Arora, Jennifer Busby et al. · Chemistry & Biology · 2014 · 148 citations

Medicine, Oncology, Pharmacology +11

MicroRNA regulation and its effects on cellular transcriptome in Human Immunodeficiency Virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts

Karolina Duskova, Pruthvi Nagilla, Hai-Son Le et al. · BMC Infectious Diseases · 2013 · 81 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Discovery, design, and synthesis of indole-based EZH2 inhibitors

Victor Gehling, Rishi G. Vaswani, Christopher G. Nasveschuk et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12