Denise Lasigliè

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way

Alessandra Piccini, Sonia Carta, Sara Tassi et al. · Proceedings of the National Academy of Sciences · 2008 · 465 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The pattern of response to anti–interleukin‐1 treatment distinguishes two subsets of patients with systemic‐onset juvenile idiopathic arthritis

Marco Gattorno, Alessandra Piccini, Denise Lasigliè et al. · Arthritis & Rheumatism · 2008 · 380 citations

Life Sciences, Immunology, Pharmacotherapy +16

Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation

Silvia Borghini, Sara Tassi, Sabrina Chiesa et al. · Arthritis & Rheumatism · 2010 · 186 citations · Full text

Medicine, Immunology, Molecular Genetics +14

The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses

Inga Bauer, Alessia Grozio, Denise Lasigliè et al. · Journal of Biological Chemistry · 2012 · 179 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Role of IL-1 Beta in the Development of Human TH17 Cells: Lesson from NLPR3 Mutated Patients

Denise Lasigliè, Elisabetta Traggiai, Silvia Federici et al. · PLoS ONE · 2011 · 127 citations · Full text

Life Sciences, Immunology, Pathobiology +17