Sonia Carta

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation

Carlo Marchetti, Benjamin J. Swartzwelter, Fabia Gamboni et al. · Proceedings of the National Academy of Sciences · 2018 · 559 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way

Alessandra Piccini, Sonia Carta, Sara Tassi et al. · Proceedings of the National Academy of Sciences · 2008 · 465 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The pattern of response to anti–interleukin‐1 treatment distinguishes two subsets of patients with systemic‐onset juvenile idiopathic arthritis

Marco Gattorno, Alessandra Piccini, Denise Lasigliè et al. · Arthritis & Rheumatism · 2008 · 380 citations

Life Sciences, Immunology, Pharmacotherapy +16

Pattern of interleukin‐1β secretion in response to lipopolysaccharide and ATP before and after interleukin‐1 blockade in patients with <i>CIAS1</i> mutations

Marco Gattorno, Sara Tassi, Sonia Carta et al. · Arthritis & Rheumatism · 2007 · 246 citations

Life Sciences, Immunology, Pathobiology +13

Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation

Silvia Borghini, Sara Tassi, Sabrina Chiesa et al. · Arthritis & Rheumatism · 2010 · 186 citations · Full text

Medicine, Immunology, Molecular Genetics +14