Riyan Chen

Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

Sylvain Latour, Romain Roncagalli, Riyan Chen et al. · Nature Cell Biology · 2003 · 270 citations

Novel Mechanism, Signal Transduction, Signaling Pathway +8

Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor

Romain Roncagalli, James E R Taylor, Shaohua Zhang et al. · Nature Immunology · 2005 · 160 citations

Host Response, Natural Killer Cells, Signal Transduction +10

Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells

Zhongjun Dong, Mario‐Ernesto Cruz‐Munoz, Ming‐Chao Zhong et al. · Nature Immunology · 2009 · 137 citations

Essential Function, Sap Family Adaptors, Cell Signaling +9

Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn

Coralie Bloch‐Queyrat, Marie‐Claude Fondanèche, Riyan Chen et al. · The Journal of Experimental Medicine · 2005 · 118 citations · Full text

Molecular Dissection of 2B4 Signaling: Implications for Signal Transduction by SLAM-Related Receptors

Riyan Chen, Francis Relouzat, Romain Roncagalli et al. · Molecular and Cellular Biology · 2004 · 117 citations · Full text

Molecular Dissection, Immunology, Nk Cells +20