Charles C. Valentine

Mutational spectra of aflatoxin B ₁ in vivo establish biomarkers of exposure for human hepatocellular carcinoma

Supawadee Chawanthayatham, Charles C. Valentine, Bogdan I. Fedeles et al. · Proceedings of the National Academy of Sciences · 2017 · 129 citations · Full text

Medicine, Oncology, Toxicology +17

Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing

Charles C. Valentine, Robert R. Young, Mark R. Fielden et al. · Proceedings of the National Academy of Sciences · 2020 · 115 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

Jesse J. Salk, Kaitlyn Loubet-Senear, Elisabeth Maritschnegg et al. · Cell Reports · 2019 · 104 citations · Full text

Medicine, Molecular Biology, Oncology +17

Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations

Danielle LeBlanc, Matthew J. Meier, Fang Yin Lo et al. · BMC Genomics · 2022 · 60 citations · Full text

Pharmacy, Genetics, Molecular Genetics +16

Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride

Annette Dodge, Danielle LeBlanc, Gu Zhou et al. · Archives of Toxicology · 2023 · 40 citations · Full text

Pharmacy, Genetics, Toxicology +16