Charles C. Valentine

Mutational spectra of aflatoxin B ₁ in vivo establish biomarkers of exposure for human hepatocellular carcinoma

Supawadee Chawanthayatham, Charles C. Valentine, Bogdan I. Fedeles et al. · Proceedings of the National Academy of Sciences · 2017 · 125 citations · Full text

Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing

Charles C. Valentine, Robert R. Young, Mark R. Fielden et al. · Proceedings of the National Academy of Sciences · 2020 · 107 citations · Full text

Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

Jesse J. Salk, Kaitlyn Loubet-Senear, Elisabeth Maritschnegg et al. · Cell Reports · 2019 · 101 citations · Full text

Pathology, Gynecology, Clonal Tp53 Mutations +18

Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations

Danielle P M LeBlanc, Matthew J. Meier, Fang Yin Lo et al. · BMC Genomics · 2022 · 55 citations · Full text

Mutation Susceptibility, Genetics, Genetic Epidemiology +18

Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride

Annette Dodge, Danielle P M LeBlanc, Gu Zhou et al. · Archives of Toxicology · 2023 · 36 citations · Full text