Simone Giacometti

Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

Gopika G. Nair, Jennifer S. Liu, Holger A. Russ et al. · Nature Cell Biology · 2019 · 475 citations · Full text

Regenerative Medicine, Induced Pluripotent Stem Cell, Developmental Biology +9

mTORC1-to-AMPK switching underlies β cell metabolic plasticity during maturation and diabetes

Rami Jaafar, Stella Tran, Ajit Shah et al. · Journal of Clinical Investigation · 2019 · 121 citations · Full text

Mitochondrial Degeneration, Metabolic Remodeling, Insulin Signaling +17

A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells

Frédéric Van Gool, Michelle Nguyen, Maxwell R. Mumbach et al. · Immunity · 2019 · 99 citations

Transcriptional Regulation, Signal Transduction, Cell Signaling +12

Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate

Simone Giacometti, Nour El Houda Benbahouche, Michal Domanski et al. · Cell Reports · 2017 · 88 citations · Full text

Loss of the transcription factor MAFB limits β-cell derivation from human PSCs

Ronan Russell, Phichitpol Carnese, Thomas G. Hennings et al. · Nature Communications · 2020 · 56 citations · Full text