Christian M. Stegmann

Transcriptional and Cellular Diversity of the Human Heart

Nathan R. Tucker, Mark Chaffin, Stephen J. Fleming et al. · Circulation · 2020 · 555 citations · Full text

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction

R.C. Hillig, Brice Sautier, Jens Schroeder et al. · Proceedings of the National Academy of Sciences · 2019 · 363 citations · Full text

Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy

Mark Chaffin, Irinna Papangeli, Bridget Simonson et al. · Nature · 2022 · 358 citations

Cardiac Muscle, Cardiomyopathy, Heart Failure +6

Deep learning enables genetic analysis of the human thoracic aorta

James P. Pirruccello, Mark Chaffin, Elizabeth L. Chou et al. · Nature Genetics · 2021 · 193 citations · Full text

Systems Biology, Engineering, Machine Learning +8

Inhibition of Metalloprotease Botulinum Serotype A from a Pseudo-peptide Binding Mode to a Small Molecule That Is Active in Primary Neurons

James C. Burnett, Gordon Ruthel, Christian M. Stegmann et al. · Journal of Biological Chemistry · 2006 · 106 citations · Full text