Yoshikazu Morishita

Microbial polysaccharide, HS-142-1, competitively and selectively inhibits ANP binding to its guanylyl cyclase-containing receptor

Yoshikazu Morishita, Tomoyuki Sano, Katsuhiko Ando et al. · Biochemical and Biophysical Research Communications · 1991 · 119 citations

Biochemistry, G Protein-coupled Receptor, Microbial Polysaccharide +8

RES-701-1,a novel and selective endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. I. Characterization of producing strain, fermentation, isolation, physico-chemical and biological properties.

Yoshikazu Morishita, Shigeru Chiba, Eiji Tsukuda et al. · The Journal of Antibiotics · 1994 · 60 citations · Full text

Pharmacological profile of HS-142-1, a novel nonpeptide atrial natriuretic peptide antagonist of microbial origin. I. Selective inhibition of the actions of natriuretic peptides in anesthetized rats.

Tsuneji Sano, Yoshikazu Morishita, Y Matsuda et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 49 citations

HS-142-1, a novel nonpeptide atrial natriuretic peptide (ANP) antagonist, blocks ANP-induced renal responses through a specific interaction with guanylyl cyclase-linked receptors

Yoshikazu Morishita, Tomoyuki Sano, Hiroshi Kase et al. · European Journal of Pharmacology Molecular Pharmacology · 1992 · 43 citations

Hypertension, Molecular Physiology, Signal Transduction +11

Stable expression of natriuretic peptide receptors: Effects of HS-142-1, a non-peptide ANP antagonist

Yoshio Ohyama, Kaoru Miyamoto, Yoshikazu Morishita et al. · Biochemical and Biophysical Research Communications · 1992 · 42 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +12