Tomoyuki Sano

Microbial polysaccharide, HS-142-1, competitively and selectively inhibits ANP binding to its guanylyl cyclase-containing receptor

Yoshikazu Morishita, Tomoyuki Sano, Katsuhiko Ando et al. · Biochemical and Biophysical Research Communications · 1991 · 119 citations

Biochemistry, G Protein-coupled Receptor, Microbial Polysaccharide +8

HS-142-1, a novel nonpeptide atrial natriuretic peptide (ANP) antagonist, blocks ANP-induced renal responses through a specific interaction with guanylyl cyclase-linked receptors

Yoshikazu Morishita, Tomoyuki Sano, Hiroshi Kase et al. · European Journal of Pharmacology Molecular Pharmacology · 1992 · 43 citations

Hypertension, Molecular Physiology, Signal Transduction +11

Effects of HS-142-1, a novel non-peptide ANP antagonist, on diuresis and natriuresis induced by acute volume expansion in anesthetized rats

Tomoyuki Sano, Yoshikazu Morishita, Kôji Yamada et al. · Biochemical and Biophysical Research Communications · 1992 · 36 citations

Neuropeptides, Gastrointestinal Peptide Hormone, Acute Volume Expansion +9

HS-142-1, a novel non-peptide ANP antagonist, blocks the cyclic GMP production elicited by natriuretic peptides in PC12 and NG108-15 cells

Shinichiro Toki, Yoshikazu Morishita, Tomoyuki Sano et al. · Neuroscience Letters · 1992 · 28 citations

Ng108-15 Cells, Cyclic Gmp Production, Molecular Physiology +9

HS-142-1, A novel polysaccharide of microbial origin, specifically recognizes guanylyl cyclase-linked ANP receptor in rat glomeruli

Tomoyuki Sano, Reiko Imura, Yoshikazu Morishita et al. · Life Sciences · 1992 · 22 citations

Glomerulonephritis, Biochemistry, G Protein-coupled Receptor +9