Irene Preet Bhela

A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs

Irene Preet Bhela, Alice Ranza, Federica Carolina Balestrero et al. · Journal of Medicinal Chemistry · 2022 · 51 citations · Full text

Combinatorial Chemistry, Protein Degraders, Bioorganic Chemistry +24

Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors

M. Teresa Serafini, Celia Cordero-Sánchez, Rosanna Di Paola et al. · Journal of Medicinal Chemistry · 2020 · 23 citations · Full text

Tritylamine as an Ammonia Surrogate in the Ugi Reaction Provides Access to Unprecedented 5-Sulfamido Oxazoles Using Burgess-type Reagents

Irene Preet Bhela, M. Teresa Serafini, Erika Del Grosso et al. · Organic Letters · 2021 · 18 citations · Full text

Diversity Oriented Synthesis, Engineering, Oxazole Compounds +11

STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39

Beatrice Riva, Emanuela Pessolano, Edoardo Quaglia et al. · Cell Calcium · 2022 · 16 citations · Full text

An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline

Silvio Aprile, Giorgia Colombo, M. Teresa Serafini et al. · ACS Medicinal Chemistry Letters · 2022 · 13 citations · Full text

Precision Deuteration, Redox Biology, Oxidative Stress +16