M. Teresa Serafini

Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to <i>in Vivo</i> Pharmacodynamic Activity

M. Teresa Serafini, Enza Torre, Silvio Aprile et al. · Journal of Medicinal Chemistry · 2020 · 55 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +14

A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs

Irene Preet Bhela, Alice Ranza, Federica Carolina Balestrero et al. · Journal of Medicinal Chemistry · 2022 · 51 citations · Full text

Combinatorial Chemistry, Protein Degraders, Bioorganic Chemistry +24

Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders

M. Teresa Serafini, Alessia Griglio, Silvio Aprile et al. · Journal of Medicinal Chemistry · 2018 · 42 citations · Full text

Passerini Adducts, Immunology, Pharmacotherapy +17

A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability

Magdalena Nikolaeva‐Koleva, Laura Butrón, Sara González‐Rodríguez et al. · Scientific Reports · 2021 · 30 citations · Full text

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis

Beatrice Riva, Alessia Griglio, M. Teresa Serafini et al. · Journal of Medicinal Chemistry · 2018 · 29 citations · Full text

Calcium Entry, Medicinal Chemistry, Signal Transduction +14