Giorgia Colombo

Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to <i>in Vivo</i> Pharmacodynamic Activity

M. Teresa Serafini, Enza Torre, Silvio Aprile et al. · Journal of Medicinal Chemistry · 2020 · 55 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +14

Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis

Giorgia Colombo, Nausicaa Clemente, Andrea Zito et al. · Journal of Molecular Medicine · 2020 · 54 citations · Full text

Inflammation, Extracellular Nampt, Anti-inflammatory +7

A Selective Competitive Inhibitor of Aldehyde Dehydrogenase 1A3 Hinders Cancer Cell Growth, Invasiveness and Stemness In Vitro

Edoardo Luigi Maria Gelardi, Giorgia Colombo, Francesca Picarazzi et al. · Cancers · 2021 · 44 citations · Full text

Tumor Biology, Crystal Structure, Oncology +14

A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus

Ambra A. Grolla, Riccardo Miggiano, Daniele Di Marino et al. · Journal of Biological Chemistry · 2020 · 34 citations · Full text

The Cytokine Nicotinamide Phosphoribosyltransferase (eNAMPT; PBEF; Visfatin) Acts as a Natural Antagonist of C-C Chemokine Receptor Type 5 (CCR5)

Simone Torretta, Giorgia Colombo, Cristina Travelli et al. · Cells · 2020 · 32 citations · Full text