Hemanth R. Nelvagal

mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

Michela Palmieri, Rituraj Pal, Hemanth R. Nelvagal et al. · Nature Communications · 2017 · 429 citations · Full text

Synergistic effects of treating the spinal cord and brain in CLN1 disease

Charles Shyng, Hemanth R. Nelvagal, Joshua T. Dearborn et al. · Proceedings of the National Academy of Sciences · 2017 · 68 citations · Full text

Immune cells perturb axons and impair neuronal survival in a mouse model of infantile neuronal ceroid lipofuscinosis

Janos Groh, Thomas Kühl, Chi Wang Ip et al. · Brain · 2013 · 57 citations

Partial Correction of the CNS Lysosomal Storage Defect in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis by Neonatal CNS Administration of an Adeno-Associated Virus Serotype rh.10 Vector Expressing the Human <i>CLN3</i> Gene

Dolan Sondhi, Emma Scott, Alvin Chen et al. · Human Gene Therapy · 2013 · 44 citations · Full text

Aavrh.10hcln3 Administration, Aavrh.10 Delivery, Pathology +27

Intrathecal enzyme replacement therapy improves motor function and survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis

Jui-Yun Lu, Hemanth R. Nelvagal, Lingling Wang et al. · Molecular Genetics and Metabolism · 2015 · 39 citations

Molecular Neuroscience, Developmental Biology, Medicine +5