Joshua T. Dearborn

Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration

Erik S. Musiek, Miranda M. Lim, Guangrui Yang et al. · Journal of Clinical Investigation · 2013 · 519 citations · Full text

Cerebral Redox Homeostasis, Homeostatic Mechanism, Degenerative Pathology +18

Core features of frontotemporal dementia recapitulated in progranulin knockout mice

Nupur Ghoshal, Joshua T. Dearborn, David F. Wozniak et al. · Neurobiology of Disease · 2011 · 131 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Dementia +9

Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis

Fan Liao, Yukiko Hori, Eloïse Hudry et al. · Journal of Neuroscience · 2014 · 122 citations · Full text

Immunology, Plaque Onset, Aβ Amyloidosis +18

Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target

Yedda Li, Yue Xu, Bruno A. Benítez et al. · Proceedings of the National Academy of Sciences · 2019 · 93 citations · Full text

An Anti-Neuroinflammatory That Targets Dysregulated Glia Enhances the Efficacy of CNS-Directed Gene Therapy in Murine Infantile Neuronal Ceroid Lipofuscinosis

Shannon L. Macauley, Andrew M.S. Wong, Charles Shyng et al. · Journal of Neuroscience · 2014 · 71 citations · Full text

Seizure Susceptibility, Immunology, Pathology +21