Tetsuo Uno

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 405 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Structure–activity Relationships +21

A Fully Integrated High-Throughput Screening Methodology for the Discovery of New Polyolefin Catalysts:  Discovery of a New Class of High Temperature Single-Site Group (IV) Copolymerization Catalysts

Thomas R. Boussie, Gary M. Diamond, Christopher Goh et al. · Journal of the American Chemical Society · 2003 · 220 citations

Engineering, Organic Chemistry, Chemistry +17

A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery

John E. Murphy, Tetsuo Uno, Janice D. Hamer et al. · Proceedings of the National Academy of Sciences · 1998 · 202 citations · Full text

Engineering, Glycobiology, Molecular Biology +20

<i>In vivo</i> Incorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy

Susan E. Cellitti, David H. Jones, Leanna Lagpacan et al. · Journal of the American Chemical Society · 2008 · 192 citations · Full text

Hemolytic anemia caused by Babesia gibsoni infection in dogs

Patricia A. Conrad, John W. Thomford, Itsuro YAMANE et al. · Journal of the American Veterinary Medical Association · 1991 · 184 citations · Full text

Parasitic Disease, Pathogenesis, Hematology +14