E. Allen Sickmier

Structural Basis for Polypyrimidine Tract Recognition by the Essential Pre-mRNA Splicing Factor U2AF65

E. Allen Sickmier, Katherine Frato, Haihong Shen et al. · Molecular Cell · 2006 · 189 citations · Full text

Systems Biology, Natural Sciences, Molecular Biology +8

Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes

Randy Hecht, Yuesheng Li, Jeonghoon Sun et al. · PLoS ONE · 2012 · 163 citations · Full text

Human Growth, Peptide Science, Biomedical Engineering +24

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Yuan Cheng, Ted Judd, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2011 · 136 citations · Full text

Structural Basis for Apelin Control of the Human Apelin Receptor

Yingli Ma, Yang Yue, Yanbin Ma et al. · Structure · 2017 · 129 citations · Full text

Molecular Physiology, Signal Transduction, G Protein-coupled Receptor +9

X-Ray Structure of a Rex-Family Repressor/NADH Complex Insights into the Mechanism of Redox Sensing

E. Allen Sickmier, Dimitris Brekasis, Shanthi R. Paranawithana et al. · Structure · 2005 · 85 citations · Full text

X-ray Crystallography, Redox Signaling, Biochemistry +9