Samia Hannaoui

PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases

Mathéa Pietri, Caroline Dakowski, Samia Hannaoui et al. · Nature Medicine · 2013 · 122 citations

Neurodegenerative Diseases, Signal Transduction, Alzheimer's Disease +10

Early and Non-Invasive Detection of Chronic Wasting Disease Prions in Elk Feces by Real-Time Quaking Induced Conversion

Yo Ching Cheng, Samia Hannaoui, Theodore R. John et al. · PLoS ONE · 2016 · 82 citations · Full text

Fatal Prion Disease, Animal Science, Zoonotic Disease +14

Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of CWD

Samia Hannaoui, Irina Zemlyankina, Sheng Chun Chang et al. · Acta Neuropathologica · 2022 · 53 citations · Full text

Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency

Samia Hannaoui, Sara Amidian, Yo Ching Cheng et al. · PLoS Pathogens · 2017 · 49 citations · Full text

Protein Function, Protein Assembly, Cervid Prion Protein +14

Prion Propagation and Toxicity Occur <i>In Vitro</i> with Two-Phase Kinetics Specific to Strain and Neuronal Type

Samia Hannaoui, Layal Maatouk, Nicolas Privat et al. · Journal of Virology · 2012 · 41 citations · Full text

Creutzfeldt-jakob Disease, Abnormal Prp Accumulation, Synaptic Transmission +22