Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Yingxiao Shi, Shao‐Yu Lin, Kim A. Staats, +40

Nature Medicine

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisMolecular NeuroscienceMotor NeuronsDegenerative Disease +9

Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain

Kassandra Kisler, Amy R. Nelson, Sanket Rege, +10

Nature Neuroscience

Cerebral Vascular RegulationNeurophysiologyMedicinePhysiologyVascular Biology +12

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

Angeliki M. Nikolakopoulou, Axel Montagne, Kassandra Kisler, +13

Nature Neuroscience

Neuron LossPericyte LossPleiotrophin DepletionNeurophysiologyNeuroanatomy +10

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

Zhen Zhao, Abhay P. Sagare, Qingyi Ma, +19

Nature Neuroscience

Neurodegenerative DiseasesCentral RoleBrain-immune InteractionNeuroprotectionNeuroscience +4

Electrochemical imaging of fusion pore openings by electrochemical detector arrays

Ismail M. Hafez, Kassandra Kisler, Khajak Berberian, +5

Proceedings of the National Academy of Sciences

Blood–brain barrier link to human cognitive impairment and Alzheimer’s disease

Giuseppe Barisano, Axel Montagne, Kassandra Kisler, +3

Nature Cardiovascular Research

Neurodegenerative DiseasesAlzheimer's DiseaseNeurobiology Of DiseaseBlood–brain BarrierVascular Cognitive Disorder +8

Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A

Angeliki M. Nikolakopoulou, Yaoming Wang, Qingyi Ma, +10

The Journal of Experimental Medicine

F-Actin and Myosin II Accelerate Catecholamine Release from Chromaffin Granules

Khajak Berberian, Alexis J. Torres, Qinghua Fang, +2

Journal of Neuroscience

CytoskeletonMechanotransductionCellular PhysiologyMyosin Ii FunctionBiophysics +18

Role of the synaptobrevin C terminus in fusion pore formation

Annita Ngatchou, Kassandra Kisler, Qinghua Fang, +5

Proceedings of the National Academy of Sciences

Protein SecretionMolecular BiologyCytoskeletonCellular PhysiologyMembrane Fusion +15

Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo

Amy R. Nelson, Meghana Sagare, Yaoming Wang, +3

Frontiers in Aging Neuroscience