Simon Scrace

TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation

Dafni‐Eleftheria Pefani, Daniela Paňková, Aswin Abraham et al. · Molecular Cell · 2016 · 142 citations · Full text

Signal Transduction, Developmental Biology, Signaling Pathway +5

ATM Regulates a RASSF1A-Dependent DNA Damage Response

Garth Hamilton, Karen S. Yee, Simon Scrace et al. · Current Biology · 2009 · 113 citations · Full text

Chromatin, Genetics, Genome Instability +1

Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution

Andrew Potter, Victoria Oldfield, Claire L. Nunns et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 97 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +9

JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations

Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix et al. · 2023 · 95 citations · Full text

Engineering, Genetics, Digital Pathology +24

Structure-guided design of α-amino acid-derived Pin1 inhibitors

Andrew Potter, Stuart Ray, Louisa Gueritz et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 85 citations · Full text

Molecular Docking, Molecular Pharmacology, Medicinal Chemistry +6