Concepedia

Structure-guided design of α-amino acid-derived Pin1 inhibitors

Andrew Potter, Stuart Ray, Louisa Gueritz, Claire L. Nunns, Chris Bryant, Simon Scrace, Natalia Matassova, Lisa Baker, P. Dokurno, David A. Robinson,

Bioorganic & Medicinal Chemistry Letters · 2009 · 86 citations · 19 references

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References

19

Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism

Michael B. Yaffe, Mike Schutkowski, Minhui Shen et al. · Science · 1997 · 771 citations

, , +9

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c‐Jun towards cyclin D1

Gerburg M. Wulf · The EMBO Journal · 2001 · 530 citations · Full text

, , +16

Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC

Akihide Ryo, Masafumi Nakamura, Gerburg M. Wulf et al. · Nature Cell Biology · 2001 · 465 citations

, , +6

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

Yih-Cherng Liou, Akihide Ryo, Han-kuei Huang et al. · Proceedings of the National Academy of Sciences · 2002 · 340 citations · Full text

, , +16

Selective Inactivation of Parvulin-Like Peptidyl-Prolyl <i>cis/trans</i> Isomerases by Juglone

Lars Hennig, Claudia Christner, Marc Kipping et al. · Biochemistry · 1998 · 312 citations

, , +16