Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

Joe Swift, Irena L. Ivanovska, Amnon Buxboim, +10

Science

Tissue EngineeringEngineeringTissue ElasticityCytoskeletonBiomedical Engineering +19

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells ‘feel’ outside and in?

Amnon Buxboim, Irena L. Ivanovska, Dennis E. Discher

Journal of Cell Science

EngineeringFeel ’ OutsideCytoskeletonMechanotransductionCell Biophysics +21

Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin

Amnon Buxboim, Joe Swift, Jerome Irianto, +8

Current Biology

MechanobiologyCell-matrix InteractionCell MotilityCell BiomechanicsCytoskeleton +7

How deeply cells feel: methods for thin gels

Amnon Buxboim, Karthikan Rajagopal, André EX Brown, +1

Journal of Physics Condensed Matter

Contractile Forces Sustain and Polarize Hematopoiesis from Stem and Progenitor Cells

Jae‐Won Shin, Amnon Buxboim, Kyle Spinler, +10

Cell stem cell

Progenitor CellsDevelopmental BiologyCell DivisionMedicineStem Cell Mobilization +10

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor

P.C. Dave P. Dingal, Andrew Bradshaw, Sang-Kyun Cho, +4

Nature Materials

MechanobiologyPattern FormationEngineeringFractal HeterogeneityMedicine +11

Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes

Amnon Buxboim, Jerome Irianto, Joe Swift, +4

Molecular Biology of the Cell

EngineeringMolecular BiologyCytoskeletonMechanotransductionNuclear Envelope Fluctuations +18

A Unified Linear Viscoelastic Model of the Cell Nucleus Defines the Mechanical Contributions of Lamins and Chromatin

Oren Wintner, Nivi Hirsch-Attas, Miriam Schlossberg, +5

Advanced Science

EngineeringCytoskeletonMechanotransductionCell BiophysicsCellular Physiology +19

A Single‐Step Photolithographic Interface for Cell‐Free Gene Expression and Active Biochips

Amnon Buxboim, Maya Bar‐Dagan, Veronica Frydman, +3

Small

EngineeringMolecular BiologyBiofabricationBiochip Platform TechnologyOrgan-on-a-chip +17

Cell-free protein synthesis and assembly on a biochip

Yael Heyman, Amnon Buxboim, Sharon G. Wolf, +2

Nature Nanotechnology

EngineeringCell-free Protein SynthesisBiotechnologyProtein EngineeringBiomolecular Engineering +1