Joshua H. K. Tam

The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid

Joshua H. K. Tam, Claudia Seah, Stephen Pasternak · Molecular Brain · 2014 · 76 citations · Full text

MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures

Fabiana A. Caetano, Brennan S. Dirk, Joshua H. K. Tam et al. · PLoS Computational Biology · 2015 · 55 citations · Full text

Protein Assembly, Molecular Biology, Extracellular Microvesicles +20

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

Weihao Tang, Joshua H. K. Tam, Claudia Seah et al. · Molecular Brain · 2015 · 41 citations · Full text

Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway

Joshua H. K. Tam, M. Rebecca Cobb, Claudia Seah et al. · PLoS ONE · 2016 · 23 citations · Full text

Novel Lysosome-directed Pathway, Neurodegenerative Diseases, Tyrosine Motifs +15

A dual magnetic resonance imaging/fluorescent contrast agent for Cathepsin‐D detection

Robert Ta, Mojmı́r Suchý, Joshua H. K. Tam et al. · Contrast Media & Molecular Imaging · 2012 · 17 citations