Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis

Aaron M. Robitaille, Stefan Christen, Mitsugu Shimobayashi, +7

Science

Signal TransductionSignaling PathwayBiochemistryNatural SciencesReceptor Tyrosine Kinase +12

Insulin resistance causes inflammation in adipose tissue

Mitsugu Shimobayashi, Verena Albert, Bettina Woelnerhanssen, +12

Journal of Clinical Investigation

Metabolic DisorderImmunologyPathologyInsulin SignalingObesity +18

mTORC2 Promotes Tumorigenesis via Lipid Synthesis

Yakir Guri, Marco Colombi, Eva Dazert, +8

Cancer Cell

MedicineTumor SuppressorCancer BiologyCell BiologyTumor Biology +1

GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing

Michael Filarsky, Sabine A. Fraschka, Igor Niederwieser, +7

Science

The Rapamycin-sensitive Phosphoproteome Reveals That TOR Controls Protein Kinase A Toward Some But Not All Substrates

Alexandre Soulard, Alessio Cremonesi, Suzette Moes, +3

Molecular Biology of the Cell

Molecular RegulationMolecular BiologyCytoskeletonRapamycin LeadsExtensive Coordination +16

The protein histidine phosphatase LHPP is a tumour suppressor

Sravanth K. Hindupur, Marco Colombi, Stephen R. Fuhs, +14

Nature

Protein FunctionBiochemistryNatural SciencesPathologyProtein Phosphorylation +5

Internal Sequences from Proteins Digested in Polyacrylamide Gels

Paul Jenö, Thierry Mini, Suzette Moes, +2

Analytical Biochemistry

Protein ChemistryInternal SequencesBiochemistryProtein Purification

A Major Role for the Plasmodium falciparum ApiAP2 Protein PfSIP2 in Chromosome End Biology

Christian Flueck, Richárd Bártfai, Igor Niederwieser, +7

PLoS Pathogens

GeneticsMalariaChromosome End BiologyGenomic MechanismMolecular Biology +19

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

Hong Jiang, Eric Schiffer, Zhangfa Song, +19

Proceedings of the National Academy of Sciences

Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum

Sophie C. Oehring, Ben J. Woodcroft, Suzette Moes, +12

Genome biology