Clemens K. Probst

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

Fei Liu, David Lagares, Kyoung Moo Choi et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2014 · 777 citations · Full text

Molecular Regulation, Healthy Lung Tissue, Mechanotransduction +30

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis

David Lagares, Alba Santos, Paula Grasberger et al. · Science Translational Medicine · 2017 · 221 citations · Full text

ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis

David Lagares, Parisa Ghassemi-Kakroodi, Caroline Tremblay et al. · Nature Medicine · 2017 · 165 citations · Full text

Inflammation, Fibrosis, Organ Fibrosis +5

The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis

Rachel S. Knipe, Clemens K. Probst, David Lagares et al. · American Journal of Respiratory Cell and Molecular Biology · 2017 · 116 citations

Acute Lung Injury, Inflammatory Lung Disease, Advanced Lung Disease +22

An Autotaxin/Lysophosphatidic Acid/Interleukin‐6 Amplification Loop Drives Scleroderma Fibrosis

Flavia V. Castelino, Gretchen Bain, Veronica A. Pace et al. · Arthritis & Rheumatology · 2016 · 96 citations · Full text