Concepedia

David Lagares

DL

26

Publications

3.2K

Citations

22

H-Index

2008

Active since

Affiliations

Massachusetts General Hospital(Current)

Harvard University

Consejo Superior de Investigaciones Científicas

Boston University

McGill University

David Lagares is an author at Massachusetts General Hospital specializing in medicine, cell biology, and cell signaling.

ORCID

Top concepts

Publications per year

2008–2024

26

Publications

26

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

Fei Liu, David Lagares, Kyoung Moo Choi et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2014 · 777 citations · Full text

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Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

Yue Zhang, Faezeh Vasheghani, Yinghua Li et al. · Annals of the Rheumatic Diseases · 2014 · 405 citations

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis

David Lagares, Alba Santos, Paula Grasberger et al. · Science Translational Medicine · 2017 · 221 citations · Full text

PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage

Faezeh Vasheghani, Yue Zhang, Yinghua Li et al. · Annals of the Rheumatic Diseases · 2015 · 216 citations · Full text

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis

Andrew J. Haak, Enis Kostallari, Delphine Sicard et al. · Science Translational Medicine · 2019 · 210 citations · Full text

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