Ian Ragan

TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates

John Atack, Keith A. Wafford, Spencer J. Tye et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 189 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Preclinical development of monoclonal antibodies

Kathryn Chapman, Nick Pullen, Lee Coney et al. · mAbs · 2009 · 97 citations · Full text

Pharmacy, Immunology, Pharmaceutical Biotechnology +17

7-(1,1-Dimethylethyl)-6-(2-ethyl-2 <i>H</i> -1,2,4- triazol-3-ylmethoxy)-3-(2-fluorophenyl)- 1,2,4-triazolo[4,3- <i>b</i> ]pyridazine:  A Functionally Selective γ-Aminobutyric Acid _A (GABA _A ) α2/α3-Subtype Selective Agonist That Exhibits Potent Anxiolytic Activity but Is Not Sedating in Animal Models

Robert W. Carling, Andrew Madin, Alec Guiblin et al. · Journal of Medicinal Chemistry · 2005 · 54 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Correction

Jes Olesen, Mary Baker, Tamás F. Freund et al. · Journal of Neurology Neurosurgery & Psychiatry · 2006 · 47 citations · Full text

Medicine, Orthopaedic Surgery, Pharmacology +16

Recommendations from a global cross-company data sharing initiative on the incorporation of recovery phase animals in safety assessment studies to support first-in-human clinical trials

Fiona Sewell, Kathryn Chapman, Paul Baldrick et al. · Regulatory Toxicology and Pharmacology · 2014 · 34 citations · Full text

Pharmacy, Pharmacology, Toxicology +15