Emma L. Meczes

Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2? construct allows the study of topoisomerase II? inhibitors in yeast.

Emma L. Meczes, Katherine L. Marsh, L. Mark Fisher et al. · Cancer Chemotherapy and Pharmacology · 1997 · 65 citations

Saccharomyces Cerevisiae, Topoisomerase Ii, Genetics +8

Mutagenesis of E477 or K505 in the B‘ Domain of Human Topoisomerase IIβ Increases the Requirement for Magnesium Ions during Strand Passage

Katherine L. West, Emma L. Meczes, Ronald Thorn et al. · Biochemistry · 2000 · 39 citations

Strand Passage, Genetics, Molecular Biology +16

The Impact of the Human DNA Topoisomerase II C-Terminal Domain on Activity

Emma L. Meczes, Kathryn Gilroy, Katherine L. West et al. · PLoS ONE · 2008 · 35 citations · Full text

Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms α and β

Katherine L. Marsh, Elaine Willmore, Stella Tinelli et al. · Biochemical Pharmacology · 1996 · 31 citations

Chromatin, Biochemistry, Natural Sciences +2

Specific adducts recognised by a monoclonal antibody against cisplatin-modified DNA

Emma L. Meczes, Ali Azim-Araghi, Christopher J. Ottley et al. · Biochemical Pharmacology · 2005 · 19 citations · Full text

Chromatin, Medicine, Natural Sciences +7