Mikko T. Huuskonen

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

Angeliki M. Nikolakopoulou, Axel Montagne, Kassandra Kisler et al. · Nature Neuroscience · 2019 · 408 citations

Neuron Loss, Pericyte Loss, Pleiotrophin Depletion +12

APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β

Axel Montagne, Angeliki M. Nikolakopoulou, Mikko T. Huuskonen et al. · Nature Aging · 2021 · 184 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Cyclophilin A +12

Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A

Angeliki M. Nikolakopoulou, Yaoming Wang, Qingyi Ma et al. · The Journal of Experimental Medicine · 2021 · 119 citations · Full text

Neuron-astrocyte transmitophagy is altered in Alzheimer's disease

Riikka Lampinen, Irina Belaya, Liudmila Saveleva et al. · Neurobiology of Disease · 2022 · 85 citations · Full text

Mitophagy, Oxidative Stress, Neuroinflammation +17

A “multi-omics” analysis of blood–brain barrier and synaptic dysfunction in <i>APOE4</i> mice

Giuseppe Barisano, Kassandra Kisler, Brent Wilkinson et al. · The Journal of Experimental Medicine · 2022 · 70 citations · Full text