Ella N. Hoogenboezem

Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy

Ella N. Hoogenboezem, Shrusti S. Patel, Justin H. Lo et al. · Nature Communications · 2024 · 37 citations · Full text

Engineering, Molecular Biology, Structural Optimization +17

Creation of an injectable in situ gelling native extracellular matrix for nucleus pulposus tissue engineering

Rebecca A. Wachs, Ella N. Hoogenboezem, Hammad Huda et al. · The Spine Journal · 2016 · 36 citations

Regenerative Medicine, Tissue Engineering, Engineering +11

Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes

Meredith A. Jackson, Sean K. Bedingfield, Fang Yu et al. · Biomaterials · 2018 · 35 citations · Full text

Materials Science, Nanomedicine, Dual Carrier-cargo Hydrophobization +8

Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing

Shrusti S. Patel, Ella N. Hoogenboezem, Fang Yu et al. · Biomaterials · 2023 · 22 citations · Full text

Nanoparticles, Nanomedicine, Core Polymer Optimization +9

Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers

Meredith A. Jackson, Shrusti S. Patel, Fang Yu et al. · Biomaterials · 2020 · 16 citations · Full text

Thrombopoiesis, Nanomedicine, Signal Transduction +8