Sean K. Bedingfield

Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage

Sean K. Bedingfield, Juan M. Colazo, Fang Yu et al. · Nature Biomedical Engineering · 2021 · 117 citations · Full text

Nanoparticles, Nanomedicine, Tissue Engineering +10

Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability

Kameron V. Kilchrist, Somtochukwu C. Dimobi, Meredith A. Jackson et al. · ACS Nano · 2019 · 114 citations

Tuning Ligand Density To Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction

Joseph P. Vanderburgh, Jordan Hill, Mukesh Kumar Gupta et al. · ACS Nano · 2020 · 61 citations · Full text

Top-Down Fabricated microPlates for Prolonged, Intra-articular Matrix Metalloproteinase 13 siRNA Nanocarrier Delivery to Reduce Post-traumatic Osteoarthritis

Sean K. Bedingfield, Juan M. Colazo, Martina Di Francesco et al. · ACS Nano · 2021 · 55 citations · Full text

Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes

Meredith A. Jackson, Sean K. Bedingfield, Fang Yu et al. · Biomaterials · 2018 · 35 citations · Full text

Materials Science, Nanomedicine, Dual Carrier-cargo Hydrophobization +8