Maturation and circuit integration of transplanted human cortical organoids

Omer Revah, Felicity Gore, Kevin W. Kelley, +19

Nature

Exercise plasma boosts memory and dampens brain inflammation via clusterin

Zurine De Miguel, Nathalie Khoury, Michael J. Betley, +20

Nature

Health SciencesExercise PlasmaExerciseMedicineExercise Physiology +7

Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome

Thomas Portmann, Mu Yang, Rong Mao, +20

Cell Reports

Basal GangliaSynaptic TransmissionHuman Chromosome 16P11.2Cellular NeurobiologySynaptic Signaling +22

Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

Amit U. Joshi, Nay L. Saw, Hannes Vogel, +3

EMBO Molecular Medicine

Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down Syndrome: Activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer

Mehrdad Faizi, Patrick L. Bader, Christine Tun, +8

Neurobiology of Disease

Down SyndromeKnockout MouseTs65dn Mouse ModelBehavioral NeuroscienceMedicine +7

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease

Amit U. Joshi, Nay L. Saw, Mehrdad Shamloo, +1

Oncotarget

Npas4: A Neuronal Transcription Factor with a Key Role in Social and Cognitive Functions Relevant to Developmental Disorders

Laurence Coutellier, Simret Beraki, Pooneh Memar Ardestani, +2

PLoS ONE

NeuropsychologyDevelopmental Cognitive NeuroscienceNeurodevelopmentNeuronal Transcription FactorDevelopmental Neuroscience +21

Small Molecule p75NTR Ligands Reduce Pathological Phosphorylation and Misfolding of Tau, Inflammatory Changes, Cholinergic Degeneration, and Cognitive Deficits in AβPPL/S Transgenic Mice

Thuy‐Vi V. Nguyen, Lin Shen, Lilith Vander Griend, +8

Journal of Alzheimer s Disease

Thy1‐hAPP^Lond/Swe+ mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function

Mehrdad Faizi, Patrick L. Bader, Nay L. Saw, +5

Brain and Behavior

Brain DevelopmentGeneticsAmyloid Precursor ProteinSynaptic SignalingSocial Sciences +18

Potential biomarkers to follow the progression and treatment response of Huntington’s disease

Marie‐Hélène Disatnik, Amit U. Joshi, Nay L. Saw, +4

The Journal of Experimental Medicine