Jan B. Hoek

Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

Nick I. Markevich, Jan B. Hoek, Boris Ν. Kholodenko · The Journal of Cell Biology · 2004 · 714 citations · Full text

Mitochondrial Binding of Hexokinase II Inhibits Bax-induced Cytochrome c Release and Apoptosis

John G. Pastorino, Nataly Shulga, Jan B. Hoek · Journal of Biological Chemistry · 2002 · 685 citations · Full text

Mitophagy, Apoptosis, Cell Death +17

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

Boris Ν. Kholodenko, Oleg V. Demin, Gisela Moehren et al. · Journal of Biological Chemistry · 1999 · 637 citations · Full text

Obesity Induces Expression of Uncoupling Protein-2 in Hepatocytes and Promotes Liver ATP Depletion

Kenneth D. Chavin, Shiqi Yang, Hui Lin et al. · Journal of Biological Chemistry · 1999 · 437 citations · Full text

Obesity Induces Expression, Metabolic Remodeling, Fatty Liver Disease +20

Untangling the wires: A strategy to trace functional interactions in signaling and gene networks

Boris Ν. Kholodenko, Anatoly Kiyatkin, Frank J. Bruggeman et al. · Proceedings of the National Academy of Sciences · 2002 · 433 citations · Full text

Genetics, Molecular Biology, Network Analysis +21