Michael Karin

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

Hsin‐Fang Yang‐Yen, Jean‐Claude Chambard, Yu-Lin Sun et al. · Cell · 1990 · 1.6K citations

Transcriptional Regulation, Signal Transduction, G Protein-coupled Receptor +9

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Audrey Minden, Anning Lin, François-Xavier Claret et al. · Cell · 1995 · 1.5K citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase

Antonio Rossi, Pankaj Kapahi, Gioacchino Natoli et al. · Nature · 2000 · 1.3K citations

Inflammation, Cytokine, Anti-inflammatory +6

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

Yoram Devary, Roberta A. Gottlieb, Tod Smeal et al. · Cell · 1992 · 863 citations

Signal Transduction, Src Tyrosine Kinases, Cell Regulation +7

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

Véronique Baud, Zhanguo Liu, Brydon L. Bennett et al. · Genes & Development · 1999 · 456 citations · Full text