Concepedia

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase

Antonio Rossi, Pankaj Kapahi, Gioacchino Natoli, Takayuki Takahashi, Yi Chen, Michael Karin, M. Gabriella Santoro

Nature · 2000 · 1.3K citations · 26 references

DOI

Concepts

References

26

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

, , +10

PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

Chengyu Jiang, Adrian T. Ting, Brian Seed · Nature · 1998 · 2.9K citations

, , +13

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

Cun-Yu Wang, Marty W. Mayo, Albert S. Baldwin · Science · 1996 · 2.6K citations · Full text

, , +17

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

Joseph A. DiDonato, Makio Hayakawa, David M. Rothwarf et al. · Nature · 1997 · 2.1K citations

, , +14

The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β

Min-Jean Yin, Yumi Yamamoto, Richard B. Gaynor · Nature · 1998 · 1.6K citations

, , +14