Thomas Miethke

Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells

R. Martin Vabulas, Parviz Ahmad‐Nejad, Clarissa da Costa et al. · Journal of Biological Chemistry · 2001 · 800 citations · Full text

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

Hans Häcker, Harald Mischak, Thomas Miethke et al. · The EMBO Journal · 1998 · 656 citations · Full text

Chromatin, Signal Transduction, Immunology +9

T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor.

Thomas Miethke, Claudia Wahl, Klaus Heeg et al. · The Journal of Experimental Medicine · 1992 · 585 citations · Full text

Immunotoxicology, Microbial Pathogens, Adaptive Immune System +24

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shock

Tim Sparwasser, Thomas Miethke, Grayson B. Lipford et al. · European Journal of Immunology · 1997 · 419 citations

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain–containing proteins

Christine Cirl, Andreas Wieser, Manisha Yadav et al. · Nature Medicine · 2008 · 385 citations

Inflammation, Toll-like Receptors, Molecular Immunology +14