Lloyd B. Jeffs

Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.8K citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

RNAi-mediated gene silencing in non-human primates

Tracy Zimmermann, Amy C. H. Lee, Akin Akinc et al. · Nature · 2006 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +8

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

Jennifer A. Lockridge, Lucinda Shaw, Karin S. Blanchard et al. · Nature Biotechnology · 2005 · 1.2K citations

Life Sciences, Biotechnology, Molecular Biology +12

A Scalable, Extrusion-Free Method for Efficient Liposomal Encapsulation of Plasmid DNA

Lloyd B. Jeffs, Lorne Palmer, Ellen Ambegia et al. · Pharmaceutical Research · 2005 · 307 citations

Pharmacy, Bioengineering, Biotechnology +16

Postexposure Protection of Guinea Pigs against a Lethal Ebola Virus Challenge Is Conferred by RNA Interference

Thomas W. Geisbert, Lisa E. Hensley, Elliott Kagan et al. · The Journal of Infectious Diseases · 2006 · 248 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17