Nadine Michot

Structural Basis for Human Monoglyceride Lipase Inhibition

Thomas Bertrand, Franck Augé, Jacques Houtmann et al. · Journal of Molecular Biology · 2009 · 167 citations

Life Sciences, Biochemistry, Molecular Biology +14

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

Guy Griebel, Philippe Pichat, Sandra Beeské et al. · Scientific Reports · 2015 · 110 citations · Full text

Medicine, Neuroscience, Pharmacology +17

PA700, the regulatory complex of the 26S proteasome, interferes with α‐synuclein assembly

Medeva Ghee, Ronald Melki, Nadine Michot et al. · FEBS Journal · 2005 · 96 citations · Full text

Life Sciences, Molecular Biology, Neurobiology +17

Discovery of (2<i>S</i>)-8-[(3<i>R</i>)-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2<i>H</i>-pyrimido[1,2-<i>a</i>]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Benoit Pasquier, Youssef El‐Ahmad, Bruno Filoche-Rommé et al. · Journal of Medicinal Chemistry · 2014 · 92 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery and Optimization of Pyrimidone Indoline Amide PI3Kβ Inhibitors for the Treatment of Phosphatase and Tensin Homologue (PTEN)-Deficient Cancers

Victor Certal, Jean‐Christophe Carry, Frank Halley et al. · Journal of Medicinal Chemistry · 2014 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15