Ana Serban

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations · Full text

Prpsc Synthesis, Protein Chemistry, Protein Secretion +15

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.

Stanley B. Prusiner, Darlene Groth, Ana Serban et al. · Proceedings of the National Academy of Sciences · 1993 · 465 citations · Full text

Genetics, Molecular Biology, Protein Expression +16

Structural studies of the scrapie prion protein by electron crystallography

Holger Wille, Melissa D. Michelitsch, Vincent Guénebaut et al. · Proceedings of the National Academy of Sciences · 2002 · 410 citations · Full text

Diagnosis of human prion disease

Jiri Safar, Michael D. Geschwind, Camille Deering et al. · Proceedings of the National Academy of Sciences · 2005 · 271 citations · Full text

Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis

Michael P. McKinley, R. Meyer, L Kenaga et al. · Journal of Virology · 1991 · 255 citations · Full text

Detergent Extraction, Biomanufacturing, Engineering +11