High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer

Amrita Datta, Hogyoung Kim, Lauren McGee, +9

Scientific Reports

Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells

Amrita Datta, Hogyoung Kim, Madhu Lal, +7

Cancer Letters

Hnrnp H1MedicineExosome BiogenesisManumycin AAnti-cancer Agent +7

Dysregulation of miR-212 Promotes Castration Resistance through hnRNPH1-Mediated Regulation of AR and AR-V7: Implications for Racial Disparity of Prostate Cancer

Yijun Yang, Dingwu Jia, Hogyoung Kim, +11

Clinical Cancer Research

Nrf1 and Nrf2 Transcription Factors Regulate Androgen Receptor Transactivation in Prostate Cancer Cells

Michelle Schultz, Sharika S. Hagan, Amrita Datta, +5

PLoS ONE

Prostate Cancer CellsCancer BiologyPersistent Androgen ReceptorTumor BiologyOxidative Stress +14

Nelfinavir targets multiple drug resistance mechanisms to increase the efficacy of doxorubicin in MCF-7/Dox breast cancer cells

Geetika Chakravarty, Aditi Mathur, Pallavi Mallade, +6

Biochimie

Breast OncologyHealth SciencesMedicineImmunologyBreast Cancer +6

Collagenase Clostridium histolyticum (Xiaflex) for the Treatment of Urethral Stricture Disease in a Rat Model of Urethral Fibrosis

Premsant Sangkum, Faysal A. Yafi, Hogyoung Kim, +8

Urology

Urethral FibrosisUrologyFibrosisUrological ResearchPathology +5

Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma

Jacob Greenberg, Hogyoung Kim, Ahmed A. Moustafa, +5

Scientific Reports

Selective targeting of FAK–Pyk2 axis by alpha-naphthoflavone abrogates doxorubicin resistance in breast cancer cells

Amrita Datta, Nobel Bhasin, Hogyoung Kim, +6

Cancer Letters

Drug TargetingFak–pyk2 AxisMedicineBreast Cancer CellsCancer Cell Biology +8

Nanotechnology combined therapy: tyrosine kinase‐bound gold nanorod and laser thermal ablation produce a synergistic higher treatment response of renal cell carcinoma in a murine model

James T. Liu, Caleb Abshire, Connor Carry, +11

British Journal of Urology

Effect of adipose tissue-derived stem cell injection in a rat model of urethral fibrosis

Premsant Sangkum, Faysal A. Yafi, Hogyoung Kim, +7

Canadian Urological Association Journal