Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance

Jean-Philippe Bastard, Martine Caron, Hubert Vidal, +10

The Lancet

Insulin ResistanceMetabolic SyndromeMetabolic DisorderPhysiologyImmunology +11

Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone

Claire Lagathu, Jean‐Philippe Bastard, Martine Auclair, +3

Biochemical and Biophysical Research Communications

InflammationMetabolic SyndromeObesityMetabolic DisorderIl-6 Secretion +11

The HIV Protease Inhibitor Indinavir Impairs Sterol Regulatory Element-Binding Protein-1 Intranuclear Localization, Inhibits Preadipocyte Differentiation, and Induces Insulin Resistance

Martine Caron, Martine Auclair, Corinne Vigouroux, +3

Diabetes

Perilipin Deficiency and Autosomal Dominant Partial Lipodystrophy

Sheetal Gandotra, Caroline Le Dour, William Bottomley, +15

New England Journal of Medicine

ObesityMetabolic SyndromeLipid SynthesisBiochemistryMetabolic Disorder +13

Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence

Michel Caron, Martine Auclair, Bruno Donadille, +8

Cell Death and Differentiation

Premature Cellular SenescenceBiochemistryA-type LaminsDegenerative PathologyCytoskeleton +5

Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene

Corinne Vigouroux, Martine Auclair, Emmanuelle Dubosclard, +4

Journal of Cell Science

GeneticsMolecular BiologyPathologyMolecular GeneticsCytoskeleton +14

PIK3R1 Mutations Cause Syndromic Insulin Resistance with Lipoatrophy

Christel Thauvin‐Robinet, Martine Auclair, Laurence Duplomb, +25

The American Journal of Human Genetics

Metabolic SyndromeGeneticsDiabetesMedicineInsulin Signaling +1

Estrogens inhibit copper and cell-mediated modification of low density lipoprotein

Cécile Mazière, Martine Auclair, M. F. Ronveaux, +3

Atherosclerosis

Low Density LipoproteinOxysterolBiochemistryMedicineGynecology +8

Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation

Martine Caron, Martine Auclair, Hélène Sterlingot, +2

AIDS

New Metabolic Phenotypes in Laminopathies:<i>LMNA</i>Mutations in Patients with Severe Metabolic Syndrome

Aurélie Decaudain, Marie‐Christine Vantyghem, Bruno Guerci, +11

The Journal of Clinical Endocrinology & Metabolism