Benoît Bestgen

Rational Design, Synthesis, and Biological Evaluation of 7-Azaindole Derivatives as Potent Focused Multi-Targeted Kinase Inhibitors

Bénédicte Daydé-Cazals, Bénédicte Fauvel, Mathilde Singer et al. · Journal of Medicinal Chemistry · 2016 · 48 citations · Full text

Combinatorial Chemistry, Chemoprevention Strategy, Focused Mtki +20

4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors

Laurent Gavara, Laurent Sevaille, Filomena De Luca et al. · European Journal of Medicinal Chemistry · 2020 · 42 citations · Full text

4-Amino-1,2,4-triazole-3-thione-derived Schiff Bases, Medicinal Chemistry, Biochemistry +6

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors

Irina Kufareva, Benoît Bestgen, P. Brear et al. · Scientific Reports · 2019 · 33 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Protein Function +15

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site

Benoît Bestgen, Isabelle Krimm, Irina Kufareva et al. · Journal of Medicinal Chemistry · 2019 · 32 citations · Full text

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action

Benoît Bestgen, Irina Kufareva, Wei-Guang Seetoh et al. · Journal of Medicinal Chemistry · 2019 · 26 citations · Full text