Activation of β-Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice

Junyan Tao, Diego F. Calvisi, Sarangarajan Ranganathan, +12

Gastroenterology

Tumor BiologyHepatologyHuman HepatoblastomaMedicineLiver Physiology +8

Beta-Catenin Activation Promotes Liver Regeneration after Acetaminophen-Induced Injury

Udayan Apte, Sucha Singh, Gang Zeng, +4

American Journal Of Pathology

HepatologyMedicineLiver PhysiologyHepatotoxicityAcetaminophen-induced Injury +4

Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations

Adeola O. Adebayo Michael, Sungjin Ko, Junyan Tao, +22

Cell Metabolism

OncologyMedicinePharmacologyCancer Cell BiologyCancer Biology +7

Accelerated Liver Regeneration and Hepatocarcinogenesis in Mice Overexpressing Serine-45 Mutant β-Catenin

Kari Nejak‐Bowen, Michael D. Thompson, Sucha Singh, +5

Hepatology

Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes

Jacquelyn O. Russell, Wei‐Yu Lu, Hirohisa Okabe, +6

Hepatology

Endothelial Wnts regulate β‐catenin signaling in murine liver zonation and regeneration: A sequel to the Wnt–Wnt situation

Morgan Preziosi, Hirohisa Okabe, Minakshi Poddar, +2

Hepatology Communications

Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point‐mutant β‐catenin

Junyan Tao, Emily Xu, Yifei Zhao, +7

Hepatology

siRNA-Mediated β-Catenin Knockdown in Human Hepatoma Cells Results in Decreased Growth and Survival

Gang Zeng, Udayan Apte, Benjamin Cieply, +2

Neoplasia

NOTCH-YAP1/TEAD-DNMT1 Axis Drives Hepatocyte Reprogramming Into Intrahepatic Cholangiocarcinoma

Shikai Hu, Laura Molina, Junyan Tao, +13

Gastroenterology

Tumor BiologyHepatologyBiliary CancerLiver PhysiologyHepatobiliary Tumor +5

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

Shikai Hu, Silvia Liu, Yu Bian, +10

Cell Reports Medicine

Endothelial CellsSpatial OmicsTranscriptional RegulationSignaling PathwayCell Regulation +20