Lata T. Gooljarsingh

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues

Lata T. Gooljarsingh, Christine Fernandes, Kang Yan et al. · Proceedings of the National Academy of Sciences · 2006 · 118 citations · Full text

Biochemical Rationale, Drug Target, Drug Resistance +19

Rational Design, Synthesis, Evaluation, and Crystal Structure of a Potent Inhibitor of Human GAR Tfase:  10-(Trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic Acid^,

Yan Zhang, Joel Desharnais, Thomas H. Marsilje et al. · Biochemistry · 2003 · 46 citations

Characterization of an exosite binding inhibitor of matrix metalloproteinase 13

Lata T. Gooljarsingh, Ami S. Lakdawala, Frank T. Coppo et al. · Protein Science · 2007 · 43 citations · Full text

Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of GAR Tfase or AICAR Tfase

Dale L. Boger, Nancy-Ellen Haynes, Mark S. Warren et al. · Bioorganic & Medicinal Chemistry · 1997 · 22 citations

Medicinal Chemistry, Medicine, Gar Tfase +10

Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors

Dale L. Boger, Monica J. Kochanny, Hui Cai et al. · Bioorganic & Medicinal Chemistry · 1998 · 18 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9