Elizabeth A. Vecchio

Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity

Alisa Glukhova, David M. Thal, Thi Nguyen et al. · Cell · 2017 · 288 citations · Full text

Medicine, Biochemistry, Pharmacology +13

Ligand-Independent Adenosine A2B Receptor Constitutive Activity as a Promoter of Prostate Cancer Cell Proliferation

Elizabeth A. Vecchio, C. Y. R. Tan, Karen J. Gregory et al. · Journal of Pharmacology and Experimental Therapeutics · 2016 · 63 citations

Medicine, Oncology, Pharmacology +16

Role of the Second Extracellular Loop of the Adenosine A1 Receptor on Allosteric Modulator Binding, Signaling, and Cooperativity

Thi Nguyen, Elizabeth A. Vecchio, Trayder Thomas et al. · Molecular Pharmacology · 2016 · 60 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Capadenoson, a clinically trialed partial adenosine A 1 receptor agonist, can stimulate adenosine A 2B receptor biased agonism

Jo‐Anne Baltos, Elizabeth A. Vecchio, Matthew Harris et al. · Biochemical Pharmacology · 2017 · 47 citations

Life Sciences, Pharmacology, Pharmacotherapy +10

The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling

Elizabeth A. Vecchio, Chung Hui Chuo, Jo‐Anne Baltos et al. · Biochemical Pharmacology · 2016 · 36 citations

Life Sciences, Molecular Biology, Pharmacology +15