Jo‐Anne Baltos

Structure of the adenosine-bound human adenosine A1 receptor–Gi complex

Christopher J. Draper-Joyce, Maryam Khoshouei, David M. Thal et al. · Nature · 2018 · 329 citations

Molecular Pharmacology, Signal Transduction, Biochemistry +4

Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination

Yi-Lynn Liang, Peishen Zhao, Christopher J. Draper-Joyce et al. · ACS Pharmacology & Translational Science · 2018 · 149 citations · Full text

Protein Chemistry, Agonist-gpcr-g Protein Complexes, Signal Transduction +12

Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist

Céline Valant, Lauren T. May, Luigi Aurelio et al. · Proceedings of the National Academy of Sciences · 2014 · 109 citations · Full text

Quantification of adenosine A 1 receptor biased agonism: Implications for drug discovery

Jo‐Anne Baltos, Karen J. Gregory, Paul J. White et al. · Biochemical Pharmacology · 2015 · 72 citations

Drug Target, Signal Transduction, Biochemistry +7

Structure-based discovery of selective positive allosteric modulators of antagonists for the M ₂ muscarinic acetylcholine receptor

Magdalena Korczynska, Mary J. Clark, Céline Valant et al. · Proceedings of the National Academy of Sciences · 2018 · 71 citations · Full text