Christopher W. Schultz

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse et al. · Cancer Cell · 2021 · 177 citations · Full text

Medicine, Molecular Biology, Oncology +14

Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes

Lőrinc Sándor Pongor, Christopher W. Schultz, Lorenzo Rinaldi et al. · Cancer Discovery · 2023 · 116 citations · Full text

Medicine, Genetics, Oncology +17

Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents

Ukhyun Jo, Ilya S. Senatorov, Astrid Zimmermann et al. · Molecular Cancer Therapeutics · 2021 · 111 citations · Full text

Medicine, Oncology, Pharmacology +15

Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models

Delphine Lissa, Nobuyuki Takahashi, Parth Desai et al. · Nature Communications · 2022 · 111 citations · Full text

Medicine, Molecular Biology, Oncology +17

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis

Marta Palomo-Irigoyen, Marta Iruarrizaga‐Lejarreta, Adrián Barreira-Manrique et al. · Journal of Clinical Investigation · 2020 · 58 citations · Full text

Medicine, Molecular Biology, Oncology +17